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03-Oct-2017 01:41

This constellation of symptoms is described by the mnemonic “PARESIS”: lurred speech.2 The ocular abnormality is manifested as Argyll-Robertson pupils (small, irregular pupils bilaterally, nonreactive to light but reactive to accommodation).While syphilitic meningitis can develop in tertiary syphilis, it more commonly occurs in earlier stages of the disease. Other dilemmas may be encountered in the treatment of patients who have concurrent human immunodeficiency virus infection. Penicillin is the only effective drug for neurosyphilis; oral desensitization should be accomplished before treatment of penicillin-allergic patients.The symptoms of primary syphilis become evident about three weeks after infection, although the onset of symptoms may range from three to 90 days.2 One or more characteristic chancres erupt at the site of inoculation.

In addition, the presence of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) has raised other concerns about the diagnosis and treatment of this disease.The VDRL and RPR, respectively, are reactive in 78 percent and 86 percent of patients with primary syphilis.8 They become positive within approximately four to six weeks after infection or one to three weeks after the appearance of the primary lesion.



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